Professor In Residence
M_PEDS-CRITICAL CARE
+1 415 476-1034
Publications
Letter of Concern from the Association of Academic Chairs of Emergency Medicine Regarding ACGME Proposed Changes.
The western journal of emergency medicine
Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity.
Nature communications
Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus.
Cell reports. Medicine
Dynamic fibroblast-immune interactions shape wound healing after brain injury.
bioRxiv : the preprint server for biology
Associations of social and cognitive-behavioral variables with disinhibited eating and anxiety: An ecological momentary assessment study.
The International journal of eating disorders
A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models.
Cell reports
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
The Journal of biological chemistry
Structural and molecular basis of choline uptake into the brain by FLVCR2.
bioRxiv : the preprint server for biology
APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Nature immunology
Radial glia promote microglial development through integrin α V β 8 -TGFβ1 signaling.
bioRxiv : the preprint server for biology
Photoinduced bidirectional switching in lipid membranes containing azobenzene glycolipids.
Scientific reports
Finding the right tool: a comprehensive evaluation of microglial inducible cre mouse models.
bioRxiv : the preprint server for biology
Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity.
Environmental science: atmospheres
The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research.
Stem cell reports
Microglia are involved in the protection of memories formed during sleep deprivation.
Neurobiology of sleep and circadian rhythms
Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice.
Translational stroke research
Surface-controlled spatially heterogeneous physical properties of a supramolecular gel with homogeneous chemical composition.
Chemical science
Enrichment of Vascular Fragments from Mouse Embryonic Brains for Endothelial Cell Analysis.
Bio-protocol
CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.
Nature neuroscience
Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier.
The Journal of clinical investigation
Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of β-Catenin Signaling.
Arteriosclerosis, thrombosis, and vascular biology
Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction.
The Journal of experimental medicine
An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins.
PloS one
Reversible restructuring of supported Au nanoparticles during butadiene hydrogenation revealed by operando GISAXS/GIWAXS.
Chemical communications (Cambridge, England)
Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature.
Cell reports
Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
The αvβ1 integrin plays a critical in vivo role in tissue fibrosis.
Science translational medicine
LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation.
The Journal of cell biology
Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.
Development (Cambridge, England)
Carbohydrate conformation and lipid condensation in monolayers containing glycosphingolipid Gb3: influence of acyl chain structure.
Biophysical journal
Mesangial cell αvβ8-integrin regulates glomerular capillary integrity and repair.
American journal of physiology. Renal physiology
Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Nature medicine
Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality.
Disease models & mechanisms
Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.
PLoS biology
Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Analysis of genomewide association signals for nonsyndromic cleft lip/palate in a Kenya African Cohort.
American journal of medical genetics. Part A
From death to recovery following hypoxia ischemia: if TGFbeta is a central regulator, is integrin beta8 the switch?
Neurotoxicity research
Distribution of orofacial clefts and frequent occurrence of an unusual cleft variant in the Rift Valley of Kenya.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association